万艾可提前多久吃？ 第一次吃万艾可吃多少？
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\u4f1f\u54e5(\u4e07\u827e\u53efViagra)\uff0c\u5373\u82f1\u6587\u540d\u201cViagra\u201d\u7684\u4e2d\u6587\u97f3\u8bd1\uff0cViagra\u6b63\u5f0f\u7684\u5546\u54c1\u4e2d\u6587\u540d\u4e3a\u201c\u4e07\u827e\u53ef\u201d\u3002 Viagra\u662f\u7531\u7f8e\u56fd\u8f89\u745e\u516c\u53f8\u7814\u53d1\u7684\u4e00\u79cd\u53e3\u670d\u6cbb\u7597ED\u7684\u836f\u7269\uff0c\u6709\u6548\u6210\u5206\u4e3aSildenafil\uff08\u897f\u5730\u90a3\u975e\uff09\u3002\u6700\u521d\uff0c\u4f5c\u4e3a\u6cbb\u7597\u5fc3\u7ede\u75db\u7684\u836f\u7269\uff0c\u540e\u6765\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u53d1\u73b0\u5bf9\u6cbb\u7597\u7537\u6027\u52c3\u8d77\u529f\u80fd\u969c\u788d\u66f4\u52a0\u6709\u6548\u3002\u8be5\u836f\u7269\u5f00\u521b\u4e86\u7537\u6027\u6027\u529f\u80fd\u969c\u788d\u7684\u836f\u7269\u6cbb\u7597\u7684\u65b0\u65f6\u4ee3\uff0c\u5f53\u5e74\u53d1\u73b0\u201c\u4f1f\u54e5\u201d\u6240\u6d89\u53ca\u7684\u4f5c\u7528\u539f\u7406\u7684\u4e09\u4f4d\u79d1\u5b66\u5bb6\u5747\u57281998\u5e74\u83b7\u5f97\u8bfa\u8d1d\u5c14\u533b\u5b66\u5956\u30021998\u5e743\u6708\u7f8e\u56fd\u4e0a\u5e02\uff0c\u4f1f\u54e5\u4e00\u8bcd\u9996\u5148\u5728\u9999\u6e2f\u4f20\u64ad\u5f00\u6765\u968f\u5373\u8fdb\u5165\u5927\u9646\u30022000\u5e747\u6708Viagra\u88ab\u6279\u51c6\u5728\u4e2d\u56fd\u4ee5\u5904\u65b9\u836f\u4e0a\u5e02\uff0c\u786e\u5b9a\u540d\u79f0\u4e3a\u4e07\u827e\u53ef\uff0c2001\u5e749\u6708\u56fd\u5bb6\u77e5\u8bc6\u4ea7\u6743\u5c40\u6279\u51c6\u53ef\u5728\u4e2d\u56fd\u7684\u4f7f\u7528\u4e13\u5229\u6743\uff0c2004\u5e745\u6708\u88ab\u6279\u51c6\u5728\u836f\u5e97\u96f6\u552e\u3002 1998\u5e746\u6708\u4f1f\u54e5\u4e00\u8bcd\u88ab\u4e2d\u56fd\u672c\u571f\u5e7f\u5dde\u5a01\u5c14\u66fc\u516c\u53f8\u62a2\u6ce8\u5546\u6807\u3002\u7f8e\u56fd\u8f89\u745e\u6709\u9650\u516c\u53f8\u4e0e\u5e7f\u5dde\u5a01\u5c14\u66fc\u836f\u4e1a\u6709\u9650\u516c\u53f8\u66fe\u5c31\u201c\u4f1f\u54e5\u201d\u5546\u6807\u7684\u76f8\u5173\u7ea0\u7eb7\u8fdb\u884c\u8fc7\u591a\u5b97\u6c11\u4e8b\u3001\u884c\u653f\u8bc9\u8bbc\u3002\u6700\u7ec8\uff0c\u5e7f\u5dde\u5a01\u5c14\u66fc\u836f\u4e1a\u6709\u9650\u516c\u53f8\u83b7\u5f97\u7b2c1911818\u53f7\u201c\u4f1f\u54e5\u201d\u5546\u6807\u3002
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\u5546\u7528\u540d\uff1a\u4e07\u827e\u53ef
\u82f1\u6587\u540d\uff1aviagra
\u522b\u540d\uff1a\u4f1f\u54e5
\u5206\u5b50\u5f0f\uff1aC22H30N6O4S
\u5206\u5b50\u91cf\uff1a474.6 g/mol
\u4e3b\u8981\u6210\u5206\uff1a14-\u4e59\u6c27\u57fa-3-[5-(6,7-\u4e8c\u6c22-1-\u7532\u57fa-7-\u6c27\u4ee3-3-\u4e19\u57fa-1H-\u5421\u5511\u5e76[4,3d]\u5627\u5576)
\u6027\u72b6\uff1a\u767d\u8272\u7ed3\u6676\u6027\u7c89\u672b
\u9002\u5e94\u75c7\uff1a\u52c3\u8d77\u529f\u80fd\u969c\u788d\uff0c\u65e9\u6cc4
\u7528\u6cd5\u7528\u91cf\uff1a\u6027\u751f\u6d3b\u524d1\u5c0f\u65f6\u670d\u7528
\u4e0d\u826f\u53cd\u5e94\uff1a\u5934\u6655\u3001\u9f3b\u585e\u3001\u6d88\u5316\u4e0d\u826f\u4ee5\u53ca\u4e00\u8fc7\u6027\u7684\u89c6\u89c9\u5f02\u5e38
\u5305\u88c5\u89c4\u683c\uff1a25mg\u300150mg\u548c100mg
\u751f\u4ea7\u5382\u5546\uff1a\u8f89\u745e\u5236\u836f
\u662f\u5426\u7eb3\u5165\u533b\u4fdd\uff1a\u672a\u7eb3\u5165
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1991\u5e744\u6708\uff0c\u897f\u5730\u90a3\u975e\u7684\u4e34\u5e8a\u7814\u7a76\u6b63\u5f0f\u5ba3\u544a\u5931\u8d25\uff0c\u4f46\u53d7\u8bd5\u8005\u62a5\u544a\u7684\u4e00\u9879\u526f\u4f5c\u7528\u5f15\u8d77\u4e86\u7814\u7a76\u4eba\u5458\u7684\u6ce8\u610f\u3002\u7814\u7a76\u5458\u53d1\u73b0\uff0c\u6cbb\u7597\u8005\u5728\u9886\u8fc7\u8bd5\u836f\u4e4b\u540e\u90fd\u4e0d\u613f\u610f\u4ea4\u51fa\u4f59\u4e0b\u7684\u836f\u7269\u3002\u8ffd\u67e5\u4e4b\u4e0b\uff0c\u53d1\u73b0\u8fd9\u4e00\u79cd\u836f\u5bf9\u75c5\u8005\u7684\u6027\u751f\u6d3b\u6709\u6539\u5584\u3002\u5728\u7ecf\u8f89\u745e\u9ad8\u5c42\u8bb8\u53ef\u540e\uff0c\u7814\u7a76\u4eba\u5458\u5c31\u897f\u5730\u90a3\u975e\u5bf9\u9634\u830e\u6d77\u7ef5\u4f53\u5e73\u6ed1\u808c\u7684\u4f5c\u7528\u5c55\u5f00\u4e86\u7814\u7a76\uff0c\u5e76\u4e8e1998\u5e743\u670827\u65e5\u83b7\u5f97\u7f8e\u56fd\u8054\u90a6\u98df\u54c1\u548c\u836f\u54c1\u7ba1\u7406\u5c40\u7684\u4e0a\u5e02\u8bb8\u53ef\uff0c\u6210\u4e3a\u4ee4\u8f89\u745e\u516c\u53f8\u540d\u58f0\u5927\u566a\u7684\u4e00\u4e2a\u4ea7\u54c1\u3002
1998\u5e74\uff0c\u7f8e\u56fd\u548c\u6b27\u6d32\u7684\u98df\u54c1\u836f\u54c1\u76d1\u7ba1\u90e8\u95e8\uff08FDA\u548cEFSA\uff09\u6279\u51c6\u4e86\u897f\u5730\u90a3\u975e\uff08Viagra\uff09\u4e0a\u5e02\u6cbb\u7597ED\uff0c\u5728\u5168\u7403\u8303\u56f4\u5185\u5f15\u8d77\u4e86\u8f70\u52a8\u3002\u897f\u5730\u90a3\u975e\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u53d1\u8868\u4e8e\u9876\u7ea7\u533b\u5b66\u6742\u5fd7\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b\uff0cNew England Journal of Medicine
1999\u5e74\uff0c\u201cViagra\u201d\u4e00\u8bcd\u88ab\u82f1\u56fd\u725b\u6d25\u5927\u8bcd\u5178\u6536\u5f55\uff0c\u540c\u65f6\uff0c\u4e34\u5e8a\u7814\u7a76\u8bc1\u5b9e\u4e86\u5176\u5fc3\u8840\u7ba1\u65b9\u9762\u7684\u5b89\u5168\u6027\u3002
2000\u5e74\uff0c\u7814\u7a76\u8fdb\u4e00\u6b65\u8bc1\u5b9e\u4e86\u897f\u5730\u90a3\u975e\u5728\u8840\u538b\u65b9\u9762\u7684\u5b89\u5168\u6027\uff0c\u4ee5\u53ca\u4e0e\u964d\u538b\u836f\u7269\u5408\u7528\u7684\u5b89\u5168\u6027\u3002\u6587\u7ae0\u53d1\u8868\u4e8e\u300a\u9ad8\u8840\u538b\u6742\u5fd7\u300b\uff0cJournal of Hypertension
2001\u5e74\uff0cViagra\u5df2\u7ecf\u5728\u5168\u7403\u8d85\u8fc7100\u4e2a\u56fd\u5bb6\u83b7\u5f97\u6279\u51c6\u4e0a\u5e02\uff0c\u5e73\u5747\u6bcf\u79d2\u5904\u65b96\u7247\u3002
2002\u5e74\uff0c\u4e34\u5e8a\u4eba\u4f53\u7814\u7a76\u8fdb\u4e00\u6b65\u8bc1\u5b9e\u4e86\u897f\u5730\u90a3\u975e\u5bf9\u7cbe\u5b50\u529f\u80fd\u65e0\u5f71\u54cd\uff0c\u6587\u7ae0\u53d1\u8868\u4e8e\u300a\u82f1\u56fd\u4e34\u5e8a\u836f\u7406\u5b66\u6742\u5fd7 \u300b\uff0cBritish Journal of Clinical Pharmacology
2003\u5e74\uff0c120\u9879\u5bf9\u7167\u7814\u7a76\u8bc1\u5b9e\u897f\u5730\u90a3\u975e\u4e0d\u589e\u52a0\u5fc3\u6897/\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u98ce\u9669\uff0c\u6587\u7ae0\u53d1\u8868\u4e8e\u300a\u56fd\u9645\u4e34\u5e8a\u5b9e\u8df5\u6742\u5fd7\u300b\uff0cInternational Journal of Clinical Practice
2004\u5e74\uff0c\u7814\u7a76\u8bc1\u5b9e\uff0c\u897f\u5730\u90a3\u975e\u901a\u8fc7\u6539\u5584\u52c3\u8d77\uff0c\u6539\u5584\u60a3\u8005\u7684\u81ea\u4fe1\u5fc3\u3001\u81ea\u5c0a\u5fc3\u3001\u4e0e\u6027\u4f34\u4fa3\u7684\u5173\u7cfb\u4ee5\u53ca\u6574\u4f53\u751f\u6d3b\u8d28\u91cf\uff08SEAR \u548cQoL\uff09
2005\u5e74\uff0cViagra\u5df2\u6709\u8d85\u8fc775\u4e07\u533b\u751f\u5904\u65b9\uff0c\u8d85\u8fc72300\u4e07\u7537\u6027\u4f7f\u7528
2006\u5e74\uff0c\u7814\u7a76\u8fdb\u4e00\u6b65\u8bc1\u5b9eViagra\u5e2e\u52a9\u7537\u6027\u8fbe\u5230\u7b2c4\u7ea7\u52c3\u8d77\u786c\u5ea6\uff08\u6700\u4f73\u52c3\u8d77\u786c\u5ea6\uff09\uff0c\u6587\u7ae0\u53d1\u8868\u4e8eJournal of Sexual Medicine
2007\u5e74\uff0c4\u5e74\u957f\u671f\u7814\u7a76\u8bc1\u5b9eViagra\u7684\u957f\u671f\u5b89\u5168\u6027\u548c\u957f\u671f\u7597\u6548\uff0c\u6587\u7ae0\u53d1\u8868\u4e8eTherapeutics and Clinical Risk Management
2008\u5e74\uff0c\u7814\u7a76\u8bc1\u5b9e\uff0c\u52c3\u8d77\u786c\u5ea6\u662fED\u60a3\u8005\u7684\u91cd\u8981\u6cbb\u7597\u671f\u5f85\uff0cSCORED\u7814\u7a76\u53d1\u8868\u4e8eInternational Journal of Impotence Research
2009\u5e74\uff0c\u5f69\u8d85\u7814\u7a76\u8bc1\u5b9e\uff0c100mg Viagra\u6cbb\u7597\u663e\u8457\u6539\u5584\u9634\u830e\u8840\u6d41\uff0c\u6587\u7ae0\u53d1\u8868\u4e8eJournal of Sexual Medicine
2010\u5e74\uff0c\u835f\u8403\u5206\u6790\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u5176\u5b89\u5168\u6027\uff0867\u9879\u53cc\u76f2\u5b89\u6170\u5242\u5bf9\u7167\u7814\u7a76\uff09\uff0c\u6587\u7ae0\u53d1\u8868\u4e8eInternational Journal of Clinical Practice
2011\u5e74\uff0c\u897f\u5730\u90a3\u975e\u5728Pubmed\u6570\u636e\u5e93\u6536\u5f55\u7684\u6587\u732e\u5df2\u8d85\u8fc74800\u7bc7\uff0c\u6709\u8d85\u8fc73800\u4e07\u7537\u6027\u4f7f\u7528Viagra
2012\u5e74\uff0c\u4e07\u827e\u53ef10\u7c92\u88c5\u5728\u4e2d\u56fd\u4e0a\u5e02
2013\u5e74\uff0c\u4e07\u827e\u53ef\u65b0\u54c1\u5305\u88c5\u4e0a\u5e02
\u89c4\u683c
\u5206\u5b50\u5f0f
\u56fd\u5185 1\u7c92/\u76d2(100mg/\u7c92)128\u5143\uff1b5\u7c92/\u76d2(100mg/\u7c92)495\u5143\uff1b10\u7c92/\u76d2(100mg/\u7c92)965\u5143
\u56fd\u5916 30\u7c92/\u74f6(100mg/\u7c92)240\u7f8e\u5143\uff1b4\u7c92/\u76d2(100mg/\u7c92)60\u7f8e\u5143\u3002\u4e0d\u8bba\u662f\u7b2c\u4e00\u6b21\u8fd8\u662f\u7b2c\u4e8c\u6b21\u5403\u8fd9\u4e2a\u836f\uff0c\u90fd\u8981\u4e25\u683c\u6309\u8bf4\u660e\u4e66\u7684\u5242\u91cf\u6765\u670d\u7528\u3002
绛旓細鎬х敓娲诲墠1灏忔椂宸﹀彸鏈嶇敤锛岃嵂鐗╁湪鏈嶇敤1灏忔椂鍐呰兘杈惧埌鏈澶х殑娴撳害锛屽ぇ绾4灏忔椂宸﹀彸浠ｈ阿鍑哄幓锛屾湜閲囩撼~
绛旓細涓囪壘鍙0.1g鍙互鍙戞尌鍑烘潵鐨勬晥鏋滄槸闈炲父鐨勬槑鏄剧殑锛屽浜庢敼鍠勭敺鎬ф湅鍙嬬殑銆傛у姛鑳介殰纰嶆湁鐫闈炲父涓嶉敊鐨勬晥鏋滐紝杩樺彲浠ユ湁鏁堢殑淇冭繘鐢锋ф湅鍙嬬殑鍕冭捣锛屽浜庢不鐤楃敺鎬фу姛鑳介殰纰嶆湁鐫闈炲父涓嶉敊鐨勫府鍔╋紝鍦鏈嶇敤鐨勬椂鍊欙紝涓鑸儏鍐靛缓璁鎻愬墠鍒30鍒嗛挓鍒板叚涓皬鏃跺幓鏈嶇敤锛屽湪鏈嶇敤涔嬪悗鍙互淇濊瘉鑽晥鍦ㄥ洓涓皬鏃跺埌鍏皬鏃跺乏鍙炽
绛旓細鍙﹀涓鏂归潰锛屽鏋滄槸骞寸邯姣旇緝澶х殑鎮ｈ咃紝寤鸿澶у鍙互鎻愬墠涓涓崐灏忔椂鏈嶇敤锛岃繖鏍锋參鎱㈢殑銆佺瓑鍒拌嵂鐗╄鍚告敹涔嬪悗灏辫兘鐪嬪埌姣旇緝濂界殑鏁堟灉銆傚叧浜庢瘡涓娆℃湇鐢ㄧ殑閲忓叾瀹炴槸鏈夎姹傜殑锛屼互50姣厠涓哄疁锛屼笉鑳借秴杩100姣厠鐨勯噺锛屽鏋滆秴杩100姣厠鐨勮瘽浼氬浜轰綋閫犳垚姣旇緝澶х殑浼ゅ銆傞氳繃涓婇潰杩欓儴鍒嗗唴瀹圭殑鍒嗘瀽澶у涔熼兘鏄庣櫧浜嗭紝涓囪壘鍙殑浠...
绛旓細涓鑸湪鎬х敓娲诲墠30鍒嗛挓锝1灏忔椂鏈嶇敤锛岀敱浜庤嵂鐗╁惛鏀舵參锛屽勾绾緝澶х殑鎮ｈ呴渶鎻愬墠1灏忔椂鏈嶇敤銆3銆佹帉鎻″墏閲 涓囪壘鍙娆″簲鐢ㄧ殑鎺ㄨ崘鍓傞噺涓25姣厠锛屽涓嶅鍙鍔犲埌50姣厠鎴100姣厠銆備絾浠讳綍澧炲姞鍓傞噺鐨勫仛娉曪紝閮藉簲璇ュ緱鍒板尰鐢熺殑鍚屾剰銆4銆佷笉鏄撴斁寮 鍦ㄦ湇鐢ㄤ竾鑹惧彲鐨勬偅鑰呬腑锛岄櫎涓婅堪璇尯澶栵紝鐢变簬鏈熸湜鍊艰繃楂樸佸か濡绘矡閫氬拰浜掑姩涓...
绛旓細鍓嶅崐灏忔椂鐢ㄧ儷姘村彛鏈嶏紝鏄嵂涓夊垎姣掑皯鍚冭嵂锛岃兘瑙ｅ喅闂鐨勪笉涓瀹氭槸鑽墿锛屽缓璁綘鐪嬬湅鐢蜂汉鐨勬灂杈逛功锛屻婃ц兘鍔涚殑鑷垜淇吇銆嬶紝浣犱細鏀惰幏鏇村銆
绛旓細涓囪壘鍙鍦ㄥ緢澶氬湴鏂癸紝浜轰滑绉板畠涓浼熷摜锛屼富瑕佹槸鐢ㄦ潵鎻愰珮鏀瑰杽鎬х敓娲昏川閲忕殑锛屽緢澶氱敺鎬ч兘浼氬湪闇瑕佺殑鏃跺欏幓鏈嶇敤瀹冿紝浣嗘槸鎴戜滑瑕佹敞鎰忥紝涓瀹氳鎻愬墠鏈嶇敤锛屾瘮濡傝鎻愬墠涓涓皬鏃跺崐涓皬鏃讹紝杩欐牱鎵嶄細璧峰埌搴旇鏈夌殑鏁堟灉锛屽浜庝竴浜涚敺鎬у姛鑳芥湁闅滅鐨勪汉鏉ヨ锛屼娇鐢ㄤ竾鑹惧彲鏁堟灉鏄笉閿欑殑锛屽彲浠ユ槑鏄惧湴鎻愰珮鎬х敓娲荤殑璐ㄩ噺锛屽垵宸╁浐澶涔嬮棿鐨...
绛旓細鍏充簬涓囪壘鍙鐨鏈嶇敤鏃堕棿锛屽缓璁湪鎬х敓娲诲墠30鍒嗛挓鑷1灏忔椂鏈嶇敤锛屼互渚胯嵂鐗╁湪浣撳唴鍙戞尌浣滅敤銆傚浜庡勾绾緝澶х殑鎮ｈ咃紝鍙兘闇瑕佹洿闀挎椂闂存墠鑳藉惛鏀惰嵂鐗╋紝鍥犳寤鸿鎻愬墠1灏忔椂鎴栨洿闀挎椂闂存湇鐢ㄣ傚湪浣跨敤涓囪壘鍙椂锛屽簲娉ㄦ剰浠ヤ笅鍑犵偣锛- 涓嶈壇鍙嶅簲閫氬父鏄交寰拰鐭殏鐨勶紝濡傛灉鍑虹幇锛屽潥鎸佷竴娈垫椂闂村悗閫氬父浼氭秷澶辨垨鍑忚交銆- 閬垮厤涓庢不鐤楀績鑴忕柧鐥...
绛旓細閽堝涓囪壘鍙兘寤堕暱澶氬皯鏃堕棿锛屼笓瀹惰涓猴紝搴旇鍦ㄥ噯澶囨х敓娲诲墠30鍒嗛挓鑷1灏忔椂鏈嶇敤锛屽勾绾緝澶х殑鎮ｈ咃紝闇鎻愬墠鍦ㄦх敓娲1灏忔椂鍓嶆湇鐢紝鍥犱负杩欑鑽墿鍚告敹閫熷害鎱傛瘡涓汉鐨勫惛鏀朵綋璐ㄤ篃涓嶄竴鏍凤紝鏈嶇敤涓囪壘鍙鍚庯紝杩橀渶瑕佸湪涓瀹氱殑鎬у埡婵涓嬫墠鑳藉彂鎸ユ渶澶т綔鐢ㄣ備竾鑹惧彲鐨勬渶浣虫湇鐢ㄦ椂闂翠竴鑸槸绌鸿吂鐨勬儏鍐典笅锛屾渶濂芥槸鍦ㄦ埧浜嬪墠涓ゅ皬鏃舵湇鐢...
绛旓細涓囪壘淇楃О浼熷摜锛屽畠鏄不鐤楃敺鎬ч槾鑼庡媰璧峰姛鑳介殰纰嶇殑鏈夋晥鑽墿锛屼絾涓嶈杩囬噺鏈嶇敤锛屼互鍏嶄骇鐢熶笉鑹壇浣滅敤銆備紵鍝ュ彲鍦ㄦт氦鍓嶅崐灏忔椂鏈嶇敤涓鑸潵璇达紝鏁堟灉闇瑕佹寔缁3鍒4涓皬鏃讹紝浼熷摜鏄竴绉嶅埡婵鎬ц嵂鐗┿備笉瑕佽繃搴︿緷璧栨垨杩囧害鎺ュ彈瀹冿紝濡傛灉鎮ｈ呮兂鏍规不鐨勮瘽锛屾偅鑰呭簲璇ュ幓鍖婚櫌妫鏌ュ拰娌荤枟銆備唬璐殑姣旇緝渚垮疁锛屾晥鏋滃ソ銆
绛旓細鎻愬墠鍗婂皬鏃跺悆锛岃繖绉嶈嵂鐗╁皯鍚冿紝骞虫椂鍙互鍔犲己閿荤偧銆浼熷摜鏄不鐤楃敺瀛愰槾鑼庡媰璧峰姛鑳介殰纰嶇殑鏈夋晥鑽墿銆傚叾鑻辨枃鍚嶇О涓 Sildenafil锛堣瘧鍚嶏細瑗垮湴閭ｈ姮銆佽タ澶氳姮銆佽タ鍦伴偅闈烇級 銆傝鍟嗘爣鐢辨繁鍦冲嚖鍑扮敓娲绘枃鍖栦紶濯掑箍鍛婃湁闄愬叕鍙哥嫭鍗犺鍙粰鐧戒簯灞卞埗鑽诲巶鐢ㄥ湪鍏剁敓浜х殑 閲戞垐 鏋告┘閰歌タ鍦伴偅闈炰骇鍝佷笂銆備紵鍝モ濆晢鏍囨濮嬩簬1998骞达紝杈夌憺...
