血液病什么是MDS 关于MDS血液病
\u8840\u6db2\u75c5\u4e2d\u7684MDS\u662f\u5982\u4f55\u5206\u7c7b\u7684?MDS\u662f\u9aa8\u9ad3\u589e\u751f\u5f02\u5e38\u7efc\u5408\u5f81\u3002\u636eMDS\u60a3\u8005\u5916\u5468\u8840\u548c\u9aa8\u9ad3\u7ec6\u80de\u75c5\u6001\u9020\u8840\u3001\u7279\u522b\u662f\u539f\u59cb\u7ec6\u80de\u6bd4\u4f8b\u3001\u73af\u5f62\u94c1\u7c92\u5e7c\u7ec6\u80de\u6570\u3001Auer\u5c0f\u4f53\u53ca\u5916\u5468\u8840\u5355\u6838\u7ec6\u80de\u6570\u91cf\uff0c\u5c06MDS\u5206\u4e3a5\u578b\uff1a\u96be\u6cbb\u6027\u8d2b\u8840\uff08refractory anemia\uff0cRA\uff09\u3001\u73af\u5f62\u94c1\u7c92\u5e7c\u7ec6\u80de\u6027\u96be\u6cbb\u6027\u8d2b\u8840\uff08RA with ringed sideroblasts\uff0cRAS\uff09\u3001\u96be\u6cbb\u6027\u8d2b\u8840\u4f34\u539f\u59cb\u7ec6\u80de\u589e\u591a\uff08RA with excess blasts\uff0cRAEB\uff09\u3001\u96be\u6cbb\u6027\u8d2b\u8840\u4f34\u539f\u59cb\u7ec6\u80de\u589e\u591a\u8f6c\u5316\u578b\uff08RAEB in transformation\uff0cRAEB-t\uff09\u3001\u6162\u6027\u7c92-\u5355\u6838\u7ec6\u80de\u767d\u8840\u75c5\uff08chronic myelomonocytic leukemia\uff0cCMML\uff09\u3002
\u3000\u3000\u9aa8\u9ad3\u589e\u751f\u5f02\u5e38\u7efc\u5408\u75c7\uff08 myelodysplastic syndrome, MDS\uff09\u662f\u4e00\u7ec4\u8d77\u6e90\u4e8e\u9020\u8840\u9ad3\u7cfb\u5b9a\u5411\u5e72\u7ec6\u80de\u6216\u591a\u80fd\u5e72\u7ec6\u80de\u7684\u5f02\u8d28\u6027\u514b\u9686\u6027\u75be\u60a3\uff0c\u4e3b\u8981\u7279\u5f81\u662f\u65e0\u6548\u9020\u8840\u548c\u9ad8\u5371\u6f14\u53d8\u4e3a\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff0c\u4e34\u5e8a\u8868\u73b0\u4e3a\u9020\u8840\u7ec6\u80de\u5728\u8d28\u548c\u91cf\u4e0a\u51fa\u73b0\u4e0d\u540c\u7a0b\u5ea6\u7684\u5f02\u5e38\u53d8\u5316\u3002\u5176\u5177\u4f53\u4e34\u5e8a\u8868\u73b0\u4e3a\u8d2b\u8840\uff0c\u53ef\u4f34\u6709\u611f\u67d3\u6216\u51fa\u8840\uff0c\u90e8\u5206\u75c5\u4eba\u53ef\u65e0\u75c7\u72b6\u3002\u90e8\u5206\u60a3\u8005\u53ef\u6709\u809d\uff0c\u813e\uff0c\u6dcb\u5df4\u7ed3\u8f7b\u5ea6\u80bf\u5927\uff0c\u5c11\u6570\u60a3\u8005\u53ef\u6709\u80f8\u9aa8\u538b\u75db\uff0c\u808b\u9aa8\u6216\u56db\u80a2\u5173\u8282\u75db\u3002\u8840\u8c61\u53ef\u5448\u5168\u8840\u7ec6\u80de\u51cf\u5c11\uff0c\u6216\u4efb\u4f55\u4e00\u7cfb\u53ca\u4e8c\u7cfb\u8840\u7ec6\u80de\u51cf\u5c11\u3002 1982\u5e74\u7531FAB\u534f\u4f5c\u7ec4\u5efa\u8bae\u786e\u7acb\u75c5\u540d\uff0c\u5e76\u5c06MDS\u5206\u4e3a\u4e94\u578b\uff1a\u96be\u6cbb\u6027\u8d2b\u8840\uff1b\u96be\u6cbb\u6027\u8d2b\u8840\u4f34\u73af\u72b6\u94c1\u7c92\u5e7c\u7ec6\u80de\u589e\u591a\uff1b\u96be\u6cbb\u6027\u8d2b\u8840\u4f34\u539f\u59cb\u7ec6\u80de\u589e\u591a\uff0c\u8f6c\u53d8\u4e2d\u7684\u96be\u6cbb\u6027\u8d2b\u8840\u4f34\u539f\u59cb\u7ec6\u80de\u589e\u591a\uff1b\u6162\u6027\u7c92\uff0d\u5355\u6838\u7ec6\u80de\u767d\u8840\u75c5\u3002 MDS\u53d1\u75c5\u7387\u7ea610/10\u4e07\uff5e12/10\u4e07\u4eba\u53e3\uff0c\u591a\u7d2f\u53ca\u4e2d\u8001\u5e74\u4eba\uff0c50\u5c81\u4ee5\u4e0a\u7684\u75c5\u4f8b\u536050\uff05\uff5e70\uff05\uff0c\u7537\u5973\u4e4b\u6bd4\u4e3a2\uff1a1\u3002MDS30%\uff5e60%\u8f6c\u5316\u4e3a\u767d\u8840\u75c5\u3002\u5176\u6b7b\u4ea1\u539f\u56e0\u9664\u767d\u8840\u75c5\u4e4b\u5916\uff0c\u591a\u6570\u7531\u4e8e\u611f\u67d3\uff0c\u51fa\u8840\uff0c\u5c24\u5176\u662f\u9885\u5185\u51fa\u8840\u3002
\u3000\u3000MDS\u5c5e\u4e2d\u533b\u201c\u865a\u70ed\u201d\uff0c\u201c\u8840\u75c7\u201d\uff0c\u201c\u5185\u4f24\u53d1\u70ed\u201d\uff0c\u201c\u7600\u75c7\u201d\u8303\u7574\u3002
\u3000\u3000\u3010\u75c5\u56e0\u3011
\u3000\u3000MDS\u7684\u75c5\u56e0\u5c1a\u4e0d\u660e\u786e\uff0c\u63a8\u6d4b\u662f\u7531\u4e8e\u751f\u7269\uff0c\u5316\u5b66\uff0c\u6216\u7269\u7406\u7b49\u56e0\u7d20\u5f15\u8d77\u57fa\u56e0\u7a81\u53d8\uff0c\u67d3\u8272\u4f53\u5f02\u5e38\u4f7f\u67d0\u4e2a\u6076\u53d8\u7684\u7ec6\u80de\u514b\u9686\u6027\u589e\u751f\u3002\u4e1a\u5df2\u516c\u8ba4\uff0c\u8bf1\u53d8\u5242\u5982\u75c5\u6bd2\uff0c\u67d0\u4e9b\u836f\u7269\uff08\u5982\u5316\u7597\u836f\uff09\uff0c\u8f90\u5c04\uff08\u653e\u7597\uff09\uff0c\u5de5\u4e1a\u53cd\u5e94\u5242\uff08\u5982\u82ef\uff0c\u805a\u4e59\u70ef\uff09\u4ee5\u53ca\u73af\u5883\u6c61\u67d3\u7b49\u7684\u53ef\u81f4\u764c\u4f5c\u7528\uff0c\u8bf1\u53d8\u5242\u53ef\u5f15\u8d77\u67d3\u8272\u4f53\u7684\u91cd\u6392\u6216\u57fa\u56e0\u91cd\u6392\uff0c\u4e5f\u53ef\u80fd\u53ea\u5f15\u8d77\u57fa\u56e0\u8868\u8fbe\u7684\u6539\u53d8\u5bfc\u81f4MDS\uff0e
\u3000\u3000MDS\u548c\u6025\u6027\u767d\u8840\u75c5\u4e00\u6837\uff0c\u662f\u7531\u4e00\u4e2a\u5f02\u5e38\u7684\u9020\u8840\u5e72\u7ec6\u80de\u884d\u751f\u7684\u6076\u6027\u514b\u9686\u53d1\u5c55\u8d77\u6765\u7684\u201c\u514b\u9686\u6027\u75be\u75c5\u201d\u3002\u4e3b\u8981\u7d2f\u53ca\u9ad3\u7cfb\u7ec6\u80de\uff0c\u4f7f\u9aa8\u9ad3\u7c92\uff0c\u7ea2\u53ca\u5de8\u4e09\u7cfb\u7ec6\u80de\u65e0\u6548\u75c5\u6001\u9020\u8840\uff0c\u5176\u51cb\u4ea1\u7ec6\u80de\u6570\u91cf\u660e\u663e\u589e\u52a0\u3002
\u3000\u3000\u3010\u5206\u578b\u3011
\u3000\u3000MDS\u5206\u4e3a\u539f\u53d1\u6027\u4e0e\u7ee7\u53d1\u6027
\u3000\u3000\u3010\u4e34\u5e8a\u8868\u73b0\u3011
\u3000\u3000\u3016\u75c7\u72b6\u3017 MDS\u901a\u5e38\u8d77\u75c5\u7f13\u6162\uff0c\u5c11\u6570\u8d77\u75c5\u6025\u5267\u3002\u4e00\u822c\u4ece\u53d1\u75c5\u5f00\u59cb\u8f6c\u5316\u4e3a\u767d\u8840\u75c5\uff0c\u5728\u4e00\u5e74\u4e4b\u5185\u7ea6\u753150\uff05\u4ee5\u4e0a\u3002\u8d2b\u8840\u60a3\u8005\u536090\uff05\u3002\u5e38\u4e3a\u4e2d\u5ea6\u8d2b\u8840\uff0c\u8868\u73b0\u4e3a\u9762\u8272\u82cd\u767d\uff0c\u5934\u6655\u4e4f\u529b\uff0c\u6d3b\u52a8\u540e\u5fc3\u60b8\u6c14\u77ed\u7b49\u3002\u53d1\u70ed\u536050%\uff0c\u5176\u4e2d\u539f\u56e0\u4e0d\u660e\u6027\u53d1\u70ed\u536010\uff05\uff5e15\uff05\uff0c\u611f\u67d3\u90e8\u4f4d\u4ee5\u547c\u5438\u9053\uff0c\u809b\u95e8\u5468\u56f4\u548c\u6ccc\u5c3f\u7cfb\u4e3a\u591a\u3002\u51fa\u8840\u536020\uff05\uff0c\u5e38\u89c1\u4e8e\u547c\u5438\u9053\uff0c\u6d88\u5316\u9053\uff0c\u4e5f\u7531\u9885\u5185\u51fa\u8840\u8005\uff0c\u65e9\u671f\u7684\u51fa\u8840\u75c7\u72b6\u8f83\u8f7b\uff0c\u591a\u4e3a\u76ae\u80a4\u7c98\u819c\u51fa\u8840\uff0c\u7259\u9f88\u51fa\u8840\u6216\u9f3b\u8844\uff0c\u5973\u6027\u60a3\u8005\u53ef\u6709\u6708\u7ecf\u8fc7\u591a\u3002\u665a\u671f\u51fa\u8840\u8d8b\u52bf\u52a0\u91cd\uff0c \u8111\u51fa\u8840\u6210\u4e3a\u60a3\u8005\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\u3002
\u3000\u3000\u3016\u4f53\u75c7\u3017 \u4e00\u822c\u65e0\u7279\u6b8a\u4f53\u5f81\uff0c\u4ec5\u5c11\u6570\u75c5\u4f8b\u6709\u809d\uff0c\u813e\uff0c\u6dcb\u5df4\u7ed3\u80bf\u5927\uff0c\u813e\u810f\u80bf\u5927\u8005\u5e38\u4e3a\u4e2d\uff0c\u8f7b\u5ea6\u3002\u665a\u671f\u53ef\u6709\u80f8\u9aa8\u538b\u75db\u3002
\u3000\u3000\u3016\u5e38\u89c1\u5e76\u53d1\u75c7\u3017
\u3000\u3000\u611f\u67d3\uff1a\u6025\u6027\u767d\u8840\u75c5 MDS\u4e2dRA,RAS\u578b\u6f14\u53d8\u4e3a\u6025\u6027\u9ad3\u7ec6\u80de\u767d\u8840\u75c5\u7684\u53d1\u751f\u7387\u7ea6\u4e3a13\uff05\uff0c\u6b64\u7ec4\u75c5\u4f8b\u751f\u5b58\u671f\u8fbe50\u4e2a\u6708\uff1bMDS\u4e2dRAEB\u4e0eCMML\u7ec4\u4e2d\u5219\u670935\uff05\uff5e40\uff05\u6f14\u53d8\u4e3a\u6025\u6027\u9ad3\u7ec6\u80de\u767d\u8840\u75c5\uff0c\u4e2d\u4f4d\u751f\u5b58\u671f\u4ec514\uff5e16\u4e2a\u6708\uff0cRAEB-T\u6f14\u53d8\u4f4d\u6025\u6027\u767d\u8840\u75c5\uff0c\u4e2d\u4f4d\u751f\u5b58\u671f\u4e3a\u4e09\u4e2a\u6708\u3002
\u3000\u3000\u51fa\u8840\uff1a \u7ea6 20\uff05\u7684MDS\u60a3\u8005\u6709\u51fa\u8840\u8868\u73b0\uff0c\u5e38\u89c1\u4e8e\u76ae\u80a4\uff0c\u547c\u5438\u9053\uff0c\u6d88\u5316\u9053\u7b49\uff0c\u4e5f\u6709\u9885\u5185\u51fa\u8840\u8005\u3002
\u3000\u3000\u3010\u8bca\u65ad\u6807\u51c6\u3011
\u3000\u30001\u3001\u4e34\u5e8a\u8868\u73b0 \u4ee5\u8d2b\u8840\u75c7\u72b6\u4e3a\u4e3b\uff0c\u53ef\u517c\u6709\u53d1\u70ed\u6216\u51fa\u8840\u3002
\u3000\u30002\u3001\u8840\u8c61 \u5168\u7ec6\u80de\u51cf\u5c11\uff0c\u6216\u4efb\u4e00\uff0c\u4e8c\u7cfb\u7ec6\u80de\u51cf\u5c11\uff0c\u53ef\u6709\u5de8\u5927\u7ea2\u7ec6\u80de\uff0c\u5de8\u5927\u8840\u5c0f\u677f\uff0c\u6709\u6838\u7ea2\u7ec6\u80de\u7b49\u75c5\u6001\u9020\u8840\u8868\u73b0\uff0e
\u3000\u30003\u3001\u9aa8\u9ad3\u8c61 \u6709\u4e09\u7cfb\u6216\u4e8c\u7cfb\uff0c\u6216\u4efb\u4e00\u7cfb\u8840\u7ec6\u80de\u7684\u75c5\u6001\u9020\u8840\uff0c\u6216\u662f\u6dcb\u5df4\u6837\u5c0f\u5de8\u6838\u7ec6\u80de
\u3000\u30004\u3001\u9664\u5916\u5176\u4ed6\u4f34\u6709\u75c5\u6001\u9020\u8840\u7684\u75be\u75c5\u3002
\u3000\u30005\u3001\u6cd5\u7f8e\u82f1\uff08 FAB\uff09\u534f\u4f5c\u7ec4\u5c06MDS\u5206\u4e3a\u4e94\u578b\u3002
\u3000\u3000\u3010\u5e38\u89c4\u6cbb\u7597\u3011
\u3000\u3000\u76ee\u524d\u4e34\u5e8a\u4e0a\u4e00\u822c\u662f\u5728\u897f\u533b\u660e\u786e\u8bca\u65ad\u7684\u57fa\u7840\u4e0a\u8fdb\u884c\u8fa8\u8bc1\u6cbb\u7597\u3002 MDS-RA,RAS\u4e24\u578b\u591a\u89c1\u6c14\u8840\u4e24\u865a\uff0c\u6c14\u9634\u4e24\u865a\uff0c\u813e\u80be\u9633\u865a\uff1bRAEB\u5219\u591a\u89c1\u809d\u80be\u9634\u865a\uff1bRAEB-T\u578b\u5219\u591a\u5c06\u89c1\u4e8e\u75f0\u7600\u4e92\u963b\u7600\u8840\u8bc1\u5019\u3002\u6240\u4ee5\u6cbb\u7597\u5e94\u6309\u4e0d\u540c\u7684\u4e34\u5e8a\u8868\u73b0\u548c\u4e0d\u540c\u7684\u9636\u6bb5\u8fdb\u884c\u3002
\u3000\u3000MDS\u7531\u4e8e\u5206\u671f\u4e0d\u540c\uff0c\u6cbb\u7597\u4e0a\u5e94\u968f\u60a3\u8005\u7684\u75c5\u60c5\u91c7\u7528\u76f8\u5e94\u7684\u4e0d\u540c\u7684\u6cbb\u7597\u5bf9\u7b56\u3002RA,RAS\u4ee5\u8d2b\u8840\u4e3a\u4e3b\u75c7\uff0c\u6b64\u65f6\u91c7\u7528\u836f\u7269\u523a\u6fc0\u9aa8\u9ad3\u9020\u8840\u4e3a\u4e3b\uff0c\u517c\u4ee5\u8bf1\u5bfc\u5206\u5316\u5242\u6cbb\u7597\uff1bRAEB\u60a3\u8005\u4ee5\u5c0f\u5242\u91cf\u5316\u7597\u6216\u52a0\u8bf1\u5bfc\u5206\u5316\u5242\u6cbb\u7597\uff1b\u800c\u5bb9\u6613\u8f6c\u5316\u4e3a\u6025\u6027\u767d\u8840\u75c5\u7684RAEB-T\u5e94\u91c7\u7528\u7c7b\u4f3c\u6025\u6027\u767d\u8840\u75c5\u7684\u5e38\u89c4\u8054\u5408\u5316\u7597\u4e3a\u4e3b\u7684\u6cbb\u7597\u3002
\u3000\u3000\u3016\u523a\u6fc0\u7d20\u9020\u8840\u5242\u3017
\u3000\u3000\u9002\u7528\u4e8e RA,RAS\u578b\u3002
\u3000\u30001\u3001\u5eb7\u529b\u9f99 6\uff5e8mg/d\uff0c\u5206\u6b21\u670d\u7528\uff0c\u7597\u7a0b\u81f3\u5c113\u4e2a\u6708\uff0c\u6700\u957f\u53ef\u670d\u4e00\u5e74\u4ee5\u4e0a\u3002\u90e8\u5206\u60a3\u8005\u809d\u529f\u80fd\u4f1a\u53d7\u635f\uff0c\u53ef\u5408\u5e76\u4f7f\u7528\u8054\u82ef\u53cc\u916f\u3002\u82e5\u56e0\u809d\u529f\u80fd\u53d7\u635f\u591a\u6b21\u505c\u836f\u8005\uff0c\u53ef\u6539\u7528\u4e19\u9178\u777e\u4e38\u916e\u808c\u5185\u6ce8\u5c04\uff0c\u6bcf\u65e550\uff5e100mg\uff0c\u8fde\u7eed\u6cbb\u7597\u534a\u5e74\u4ee5\u4e0a\u65b9\u53ef\u5224\u65ad\u7597\u6548\u3002
\u3000\u30002\u3001\u6cfc\u5c3c\u677e 30\uff5e40mg/d,\u5206\u6b21\u670d\u7528\uff0c\u9002\u7528\u4e8eMDS\u5408\u5e76\u6eb6\u8840\u3002
\u3000\u3000\u3016\u8bf1\u5bfc\u5206\u5316\u5242\u3017
\u3000\u30001\u3001\u7ef4\u7532\u9178\u7c7b
\u3000\u3000\uff081\uff09 \u5168\u53cd\u5f0f\u7ef4\u7532\u9178\uff1a30\uff5e60\uff0c\u52063\u6b21\u53e3\u670d\uff0c\u7597\u7a0b\u5e94\u57283\u4e2a\u6708\u4ee5\u4e0a\uff0c\u5bf9RA\u8f83\u597d\uff0c
\u3000\u3000\uff082\uff09\u987a\u5f0f\u7ef4\u7532\u9178\uff1a
\u3000\u3000\uff083\uff09\u52063\u6b21\u53e3\u670d\uff0c\u7597\u7a0b\u81f3\u5c113\u4e2a\u6708\u3002
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\u3000\u3000\u96be\u70b9\u4e4b\u4e00\uff1a MDS\u7684\u8bca\u65ad
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\u3000\u30001\u3001\u4fdd\u8bc1 MDS\u8bca\u65ad\u7684\u53ef\u9760\u6027.
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\u3000\u30002\u3001\u5fcc\u53e3\uff0c\u9e21\u5c5e\u9633\uff0c\u52a8\u98ce\u3002 MDS\u865a\u5b9e\u5939\u6742\uff0c\u90aa\u6bd2\u5185\u58c5\u52a9\u706b\u52a8\u98ce\u4e4b\u54c1\u5b9c\u5fcc\u3002\u7279\u522b\u662f\u9634\u865a\u706b\u65fa\uff0c\u51fa\u8840,\u75f0\u6e7f\u4ea4\u963b\u8005\u5c24\u8981\u6ce8\u610f\u3002
\u3000\u30003\u3001\u51ac\u866b\u590f\u8349\u7096\u9e2d \u51ac\u866b\u590f\u8349 5g\uff0c\u9e2d75g\uff0c\u751f\u59dc3\u7247\uff0c\u9ec4\u91525g\uff0c\u6c34200ml,\u9002\u52a0\u76d0\u6cb9\u8c03\u5473\uff0c\u6587\u706b\u7096\u4e24\u5c0f\u65f6\uff0c\u996e\u6c64\u98df\u8089\u3002\u6cbb\u7597MDS\u6c14\u9634\u4e0d\u8db3\uff0c\u795e\u75b2\u4e4f\u529b\uff0c\u820c\u6de1\u7ea2\uff0c\u8109\u7ec6\u8005\u3002
\u3000\u30004\u3001\u7cbe\u795e\u8c03\u7406 \u809d\u6c14\u90c1\u7ed3\u4e0e MDS\u7684\u53d1\u75c5\u5173\u7cfb\u5bc6\u5207\uff0c\u6709\u8d44\u6599\u63d0\u51faMDS\u53d1\u75c5\u524d\u6709\u957f\u8fbe\u534a\u5e74\u4ee5\u4e0a\u7684\u8f83\u4e25\u91cd\u7684\u7cbe\u795e\u523a\u6fc0\uff0c\u56e0\u6b64\u63d0\u5021\u865a\u6000\u82e5\u8c37\uff0c\u80f8\u895f\u5f00\u9614\uff0c\u63d0\u9ad8\u4fee\u517b\uff0c\u5728\u75be\u75c5\u8c03\u5236\u7684\u8fc7\u7a0b\u4e2d\u6613\u975e\u5e38\u5173\u952e\u3002
绛旓細Mbs鍙堢О涓洪楂撳紓甯稿鐢熺患鍚堢棁锛屽畠涓昏鏄楂撳鐢熷紓甯革紝浠庤屽鑷磋传琛鍑鸿鎰熸煋鐨勭棁鐘锛屼粬鏈韩鍜岀櫧琛鐥呰〃鐜板緢鐩镐技锛岃屼笖鏋佸鏄撳悜鐧借鐥呰浆鍙橈紝涓鑸楂撳紓甯哥患鍚堢棁杩涘睍涓虹櫧琛鐥咃紝鍜岀櫧琛鐥呯殑娌荤枟鍘熷垯鍩烘湰涓婃槸涓鏍风殑锛岄氬父閮芥槸杩涜鍖栫枟锛岄楂撻犺骞茬粏鑳炵Щ妞嶅彲浠ユ牴娌 ...
绛旓細鈶ュ叾浠栧彲绱強閫犺骞茬粏鑳炵殑鐤剧梾,濡傚啀鐢熼殰纰嶆ц传琛銆佸師鍙戞ч楂撶氦缁村寲(灏ゅ叾闇瑕佷笌浼存湁绾ょ淮鍖栫殑MDS鐩搁壌e)銆佸ぇ棰楃矑娣嬪反缁嗚優鍐呰鐥(LGL)銆侀樀鍙戞х潯鐪犳ц绾㈣泲鍐呭翱鐥(PNH)銆佹ユх櫧琛鐥匸灏ゅ叾鏄即鏈夎缁嗚優鍙戣偛寮傚父鐨勫舰鎬佸鐗圭偣鐨勬偅鑰呮垨鎬ユч珦绯荤櫧琛鐥(AML)-M7]鍙婂叾浠栧厛澶╂ф垨閬椾紶鎬琛娑茬梾(濡傚厛澶╂х孩缁嗚優鐢熸垚寮傚父鎬ц传琛...
绛旓細MDS鏄竴绉嶉毦娌诲瀷琛娑茬梾锛屽垎濂藉嚑绉嶇被鍨嬶紝鍗崇劧鏄毦娌诲瀷琛娑茬梾锛屽綋鐒朵笉瀹规槗娌诲ソ锛屽彧鑳界紦瑙ｇ梾鎯咃紝瀹屽叏鏍规不锛岀洰鍓嶇殑鍖诲姘村钩杩樺緢涓嶈銆傜幇鏈夊ソ澶氬尰闄㈡妸閭ｄ簺鏌ヤ笉鍑哄師鍥犵殑琛娑茬梾閮藉綊鍒伴偅涓绫讳簡銆
绛旓細楠ㄩ珦澧炵敓寮傚父缁煎悎寰佺洰鍓嶅皻鏃犱护浜烘弧鎰忕殑娌荤枟鏂规锛屾荤殑璇存潵锛屾槸澶氱鑽墿鐨勭患鍚堟不鐤銆傚浜庨儴鍒嗙被鍨嬬殑楠ㄩ珦澧炵敓寮傚父缁煎悎寰佹偅鑰呮潵璇达紝寮傚熀鍥犻犺骞茬粏鑳炵Щ妞嶄粛鏄敮涓鍙兘娌绘剤鐨勬柟娉曘傚湪鍏蜂綋娌荤枟鏃讹紝搴旀牴鎹被鍨嬬殑涓嶅悓鑰岄夌敤涓嶅悓鐨勬不鐤楀師鍒欏拰鏂规硶銆傚浜嶳A銆丷AS锛屼互鏀寔娌荤枟涓轰富锛屽嵆褰撹传琛鎴栧嚭琛涓ラ噸鏃讹紝缁欎簣杈撴敞绾...
绛旓細MDS鏄竴绉嶅▉鑳佷汉绫诲仴搴风殑甯歌琛娑茬梾锛屽叾鍙戠梾鏈夋棩鐩婂鍔犺秼鍔匡紝杈冩ユч珦缁嗚優鐧借鐥呯殑鍙戠梾鐜囬珮3-4鍊嶃傝櫧鐒舵湁浜涚梾渚嬪彂鐥呭師鍥犱笉娓咃紝浣嗗緢澶氱梾渚嬫槸鐢变簬鐢熺墿銆佸寲瀛︽垨鐗╃悊绛夊洜绱犲紩璧风殑缁嗚優鍏嬮殕鎬у鐢熴傚洜姝わ紝搴旈噰鍙栭闃叉帾鏂斤紝鍖诲姟浜哄憳搴旇璇嗗埌婊ョ敤鑽墿鐨勫嵄瀹虫э紝浣跨敤鍖栫枟鑽鎱庨噸锛涙斁灏勬不鐤椾篃搴斾弗鏍兼妸鎻￠傚簲璇侊紱鍦ㄦ湁...
绛旓細楠ㄩ珦澧炵敓寮傚父缁煎悎鐥囩畝绉癕DS锛屾槸閫犺骞茬粏鑳炲厠闅嗘х柧鐥咃紝鍦ㄤ复搴婃不鐤椾腑锛屾垜浠妸MDS鍒嗕负浣庡嵄缁勪笌楂樺嵄缁勩備綆鍗辩粍澶氫负RA銆丷AS銆丷CMD鐥呬汉锛屼互璐涓轰富锛岃〃鐜颁负澶存檿銆佺柌鍊︿箯鍔涖佸績鎱屾皵鐭侀潰鑹茶悗榛勬垨鑻嶇櫧銆佹寚鐢叉贰鐧姐佽垖 娣¤剦缁嗭紝 娌讳互琛ヨ偩濉簿涓轰富锛岀Н鏋佷績杩涙甯歌缁嗚優鐢熸垚锛岃緟浠ヨВ姣掔閭紝鎶戝埗鐥呮佽缁嗚優鐢熸垚锛...
绛旓細浣犲ソ锛楠ㄩ珦澧炵敓寮傚父缁煎悎寰锛堢畝绉癕DS锛夊張绉扮櫧琛鐥呭墠鏈燂紝鏄寚鏌愪簺鍥犵礌鎹熶激楠ㄩ珦閫犺骞茬粏鑳炴墍寮曡捣鐨勪竴缁勪互楠ㄩ珦鐥呮侀犺銆佸鍛ㄨ涓竴绯绘垨鏁扮郴琛缁嗚優鍑忓皯鍙婂舰鎬佸紓甯稿拰鍏嶇柅鍔熻兘銆佹琛鍔熻兘闅滅涓轰富瑕佽〃鐜扮殑琛娑茬梾銆傛湰鐥呯梾鍥犲皻涓嶆槑纭紝鍙兘涓庢煇浜涘洜绱犲鐥呮瘨鎬ц倽鐐庛佽偪鐦ゆ斁鍖栫枟鍚庛佹帴瑙﹁嫰銆佹湁鏈虹７銆佹斁灏勭嚎鍙婁竴浜涚粏鑳炴瘨...
绛旓細杩欎袱绉嶇柧鐥呴兘灞炰簬琛娑茬梾锛屼絾鐩稿樊鏄緢澶х殑锛楠ㄩ珦澧炵敓寮傚父缁煎悎鐥锛圡DS锛夋槸閫犺骞茬粏鑳炲娈栧垎鍖栧紓甯告墍鑷寸殑閫犺鍔熻兘闅滅銆備富瑕佽〃鐜颁负澶栧懆琛鍏ㄨ缁嗚優鍑忓皯锛岄楂撶粏鑳炲鐢燂紝鎴愮啛鍜屽辜绋氱粏鑳炴湁褰㈡佸紓甯稿嵆鐥呮侀犺銆傚鍙戞ч楂撶槫鏄祮缁嗚優寮傚父澧炵敓鐨勬伓鎬ц偪鐦ゃ備竴绉嶈繘琛屾х殑鑲跨槫鎬х柧鐥.鍏剁壒寰佷负楠ㄩ珦娴嗙粏鑳炵槫鍜屼竴鏍畬鏁存х殑...
绛旓細楠ㄩ珦澧炵敓寮傚父缁煎悎寰锛圡DS锛夋寚鐨勬槸涓缁勫悗澶╂х殑鍏嬮殕鎬х柧鐥咃紝鍏剁壒鐐逛负鍏嬮殕鎬ч犺骞茬粏鑳炲拰绁栫粏鑳炵殑鍙戣偛寮傚父锛岃繖鍙兘瀵艰嚧鏃犳晥閫犺鍜屽鍔犺浆鍖栦负鎬ユч珦绯荤櫧琛鐥咃紙AML锛夌殑椋庨櫓銆侻DS鎮ｈ呴楂撲腑鐨勮缁嗚優鏁伴噺鍙兘澧炲鎴栨甯革紝浣嗗舰鎬佸瓨鍦ㄦ槑鏄惧紓甯革紱澶栧懆琛涓殑琛缁嗚優鏁伴噺鏄捐憲鍑忓皯銆傝灏忔澘鍑忓皯鎬х传鐧滐紙TTP锛夋槸涓绉嶄弗閲嶇殑寰...
绛旓細MDS鏄楂撳鐢熷紓甯哥患鍚堝緛銆傛嵁MDS鎮ｈ呭鍛ㄨ鍜岄楂撶粏鑳炵梾鎬侀犺銆佺壒鍒槸鍘熷缁嗚優姣斾緥銆佺幆褰㈤搧绮掑辜缁嗚優鏁般丄uer灏忎綋鍙婂鍛ㄨ鍗曟牳缁嗚優鏁伴噺锛屽皢MDS鍒嗕负5鍨嬶細闅炬不鎬ц传琛锛坮efractory anemia锛孯A锛夈佺幆褰㈤搧绮掑辜缁嗚優鎬ч毦娌绘ц传琛锛圧A with ringed sideroblasts锛孯AS锛夈侀毦娌绘ц传琛浼村師濮嬬粏鑳炲澶氾紙RA with ...
